- The LP.8.1 variant, a descendant of Omicron, now accounts for one in five cases in NSW.
- The WHO has designated it as a Variant Under Monitoring due to its mutations.
- Current vaccines are expected to remain effective against severe disease.
The LP.8.1 variant, first detected in July 2024, has been increasing in Australia, making up a significant portion of COVID-19 cases in New South Wales.
Australia has recorded around 45,000 new cases so far in 2025, though the actual number is likely higher due to underreporting. Health authorities stress the importance of vaccination, as current COVID-19 vaccines are still expected to provide strong protection against severe illness caused by LP.8.1.
WHO Monitors LP.8.1 Variant as Cases Rise in Australia
The LP.8.1 variant is a descendant of Omicron, specifically from the KP.1.1.3 lineage. It carries several mutations in its spike protein, which may impact its transmissibility and immune evasion. While it has been spreading in multiple countries, its symptoms do not appear to be more severe than previous variants.
New South Wales is seeing LP.8.1 become the third most dominant strain, accounting for nearly 20% of cases. However, hospitalization rates remain manageable, with around 260 patients currently admitted due to COVID-19. The WHO designated LP.8.1 as a Variant Under Monitoring in January 2025 due to its rapid spread.
Despite rising infections, experts believe that current COVID-19 vaccines, including the JN.1 shots, will continue to offer strong protection against severe outcomes. The true number of cases may be higher as many individuals are no longer testing or reporting their infections.
Authorities emphasize the importance of continued monitoring and vaccination efforts to curb further transmission. While LP.8.1 is spreading, its overall impact on public health is expected to be limited compared to earlier Omicron waves.
The LP.8.1 variant is spreading in Australia but is not expected to drastically alter the trajectory of the pandemic. Vaccination remains the best defense against severe illness.
“The virus continues to evolve, but our best protection remains vaccination and vigilance.” – World Health Organization